MedlinePlus Medical Encyclopedia: Factor XII (Hageman factor) deficiency

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Factor XII (Hageman factor) deficiency

Contents of this page:
Illustrations Definition Causes, incidence, and risk factors Symptoms Signs and tests	Treatment Expectations (prognosis) Complications Calling your health care provider Prevention

Illustrations

Blood clots

Definition Return to top

This is an inherited disorder that causes prolonged clotting (coagulation) of blood in a test tube without a clinical bleeding tendency, and results from a deficiency of the plasma protein factor XII.

Causes, incidence, and risk factors Return to top

Factor XII deficiency is a hrare ereditary disorder that is usually found when clotting tests are done for routine screening. It is not associated with abnormal bleeding.

Symptoms Return to top

There are usually no symptoms.

Signs and tests Return to top

Prolonged partial thromboplastin time
Abnormal factor XII assay

Treatment Return to top

Treatment is generally unnecessary.

Expectations (prognosis) Return to top

The outcome is expected to be good without treatment.

Complications Return to top

There are usually no complications.

Calling your health care provider Return to top

This condition is usually discovered by the health care provider when prolonged clotting is noticed in the process of running other laboratory tests.

Prevention Return to top

This is an inherited disorder. There is no known way to prevent it.

Update Date: 8/18/2003

Updated by: Corey Cutler, M.D., M.P.H., F.R.C.P.C, Department of Medical Oncology, Dana-Farber Cancer Institute; Instructor in Medicine, Harvard University, Boston, MA. Review provided by VeriMed Healthcare Network.

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