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Malathion

Chemical Review Manager: Anne Overstreet, 703-308-8068

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Hazard Assessment of the Organophosphates (264 KB, PDF)
FQPA Safety Factor Recommendations for the Organophosphates (79 KB, PDF)
Technical Briefing - November 9, 2000, 9 a.m. to 5 p.m. at the Radisson Hotel, 901 N. Fairfax St., Alexandria, VA.

Guidance on Cholinesterase Measures in DNT and Related Studies (178KB PDF) (10/29/01)
Frequently Asked Questions
Federal Register Notice
- F.R. Notice Vol. 65, Number 239, Pages 77624-77626
  (comment period ending February 12, 2001)
- F.R. Notice Vol. 65, Number 92, Pages 30407-30409
  (comment period ending July 10, 2000)
Revised Risk Assessments (Released 11/9/00)
- Malathion Summary
- Overview of Malathion Revised Risk Assessment
- Technical Briefing Agenda
- Technical Briefing Slide Presentation (807 KB, PDF)
- Health Effects (425 KB, PDF)
  - Occupational and Residential Exposure and Risk Assessment (492 KB, PDF)
  - Chronic Dietary Risk Assessment (35 KB, PDF)
  - Maximum Use Patterns for Malathion on Food Crops (67 KB, PDF)
  - HED's Response to Public Comments (106 KB, PDF)
  - Revised Response to Registrant's Comments (206 KB, PDF)
  - Letter from Dr. Dementi Concerning Cancer and Non-Cancer Toxicology Issues (13 KB, PDF)
  - Scientific Advisory Panel meeting report - Proposed Classification of the Human Carcinogenic Potential of Malathion (51 KB, PDF)
- Environmental Fate and Effects (598 KB, PDF)
  - EFED's Response to Public Comments (247 KB, PDF)
- Preliminary Risk Assessments (Released 5/11/00)
  - Health Effects (357 KB, PDF)
    - Product Chemistry Chapter (138 KB, PDF)
    - Residue Chemistry Chapter (472 KB, PDF)
    - Anticipated Residues for Acute and Chronic Dietary Risk from Uses being Supported for Reregistration (182 KB, PDF)
    - Review of Malathion Incident Reports (103 KB, PDF)
    - Quantitative Usage Analysis (12 KB, PDF)
    - Dietary Risk Assessment (138 KB, PDF)
    - Evaluation of the Carcinogenic Potential of Malathion (943 KB, PDF)
      - Attachments (677 KB, PDF)
    - Occupational and Residential Exposure and Risk Assessment (542 KB, PDF)
    - Toxicology Chapter (235 KB, PDF)
    - Revised NOAEL for Derivation of the Chronic Reference Dose (104 KB, PDF)
      - Correction to the Revised NOAEL for Derivation of the Chronic Reference Dose (105 KB, PDF)
    - Drinking Water Concentrations (521 KB, PDF)
    - Report of the Hazard Identification Assessment Review Committee (48 KB, PDF)
      - Attachments 1-2 (214 KB, PDF)
      - Attachments 3-18 (148 KB, PDF)
    - Report of the Hazard Identification Assessment Review Committee (229 KB, PDF)
    - Response to the HIARC Report (29 KB, PDF)
    - Evaluation of the HIARC's Reports Regarding Scientific Issues (262 KB, PDF)
    - Evaluation of the Cheminova Report Titled: A Pathology Working Group Review of Liver Slides from the 24-Month Toxicity/Oncogenicity Study in the Rat (131 KB, PDF)
    - Memo to Clark Swentzel Re: 12/22/98 HIARC Report on the External Peer Process (38 KB, PDF)
    - Memo to John Carley Re: An Assessment of the 1/13/00 HIARC Meeting (31 KB, PDF)
    - Memo to Paula Deschamp Re: Summary of Article by Ehrlich et.al. (5 KB, PDF)
  - Environmental Fate and Effects
    - Cover Memo (21 KB, PDF)
    - Part 1 (246 KB, PDF)
    - Part 2 (330 KB, PDF)
    - Appendices (70 KB, PDF)
- EPA Correspondence
  - Letter to Jellinek, Schwartz & Connolly, Inc., to Initiate 30-Day Error Correction Comment Period (5 KB, PDF)
  - HED's Response to Cheminova's Comments (69 KB, PDF)
  - EFED's Response to Cheminova's Comments (18 KB, PDF)
  - Dr. Brian Dementi's Response to the Dobozy Report (1 MB, PDF)
- Registrant Comments

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