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Summaries of Newsworthy Clinical Trial Results

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Supportive Care Trial Results
1.  Zoledronic Acid Reduces Bone Complications of Advanced Prostate Cancer
(Posted: 06/21/2002, Updated: 06/14/2004) - In a study published in the October 2, 2002, issue of the Journal of the National Cancer Institute, patients with prostate cancer that had spread to the bones had fewer fractures and other bone complications when they took a new drug, zoledronic acid (also called zolendronate or Zometa®) than when they took a placebo.

2.  Added to Standard Anti-Nausea Medicines, Aprepitant Improves Results
(Posted: 10/28/2003) - Drugs used to treat nausea and vomiting are called anti-emetics. Two studies examined a new anti-emetic drug called aprepitant (brand name EMEND®) in patients undergoing cancer treatment. In both studies, patients who received aprepitant suffered less nausea and vomiting than patients who received standard anti-emetic drugs. The studies were from the Journal of Clinical Oncology, published online Oct. 14, 2003; in print issue Nov. 15, 2003.

3.  Surgery Helps Relieve Spinal Cord Compression Caused by Metastatic Cancer
(Posted: 06/02/2003) - Surgery followed by radiation is more effective than radiation alone in treating spinal cord compression caused by metastatic cancer.

4.  Implantable Device May Offer Better Pain Management
(Posted: 10/23/2002) - Patients with advanced cancer who used an implantable drug-delivery device to control their pain had better pain relief, fewer toxic side effects, and better survival than patients who received intensive medical pain management, researchers reported in the October 1, 2002, issue of the Journal of Clinical Oncology.

5.  Stress Management Training for Cancer Patients
(Posted: 08/07/2002) - A self-administered stress management training program did a better job of helping patients cope with the adverse effects of chemotherapy than a one-hour program in which training was given by mental health professionals, according to the June 15, 2002, Journal of Clinical Oncology.
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