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Radon 222 (CASRN 14859-67-7)

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0275

Radon 222; CASRN 14859-67-7

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of chronic toxicity data by U.S. EPA health scientists from several Program Offices and the Office of Research and Development. The summaries presented in Sections I and II represent a consensus reached in the review process. Background information and explanations of the methods used to derive the values given in IRIS are provided in the Background Documents.

STATUS OF DATA FOR Radon 222

File First On-Line 09/30/1987

Category (section)
Status
Last Revised
Oral RfD Assessment (I.A.) no data  
Inhalation RfC Assessment (I.B.) no data  
Carcinogenicity Assessment (II.) withdrawn 07/01/1993

_I.  Chronic Health Hazard Assessments for Noncarcinogenic Effects

_I.A. Reference Dose for Chronic Oral Exposure (RfD)

Substance Name -- Radon 222
CASRN -- 14859-67-7

Not available at this time.

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_I.B. Reference Concentration for Chronic Inhalation Exposure (RfC)

Substance Name -- Radon 222
CASRN -- 14859-67-7

Not available at this time.

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_II.  Carcinogenicity Assessment for Lifetime Exposure

Substance Name -- Radon 222
CASRN -- 14859-67-7

The carcinogen assessment summary for this substance has been withdrawn following further review. A new carcinogen summary is in preparation by the CRAVE Work Group.

Agency Work Group Review -- 12/17/1986, 11/30/1988, 03/01/1989, 05/04/1989, 10/21/1992, 02/02/1993, 03/31/1993

Screening-Level Literature Review Findings -- A screening-level review conducted by an EPA contractor of the more recent toxicology literature pertinent to the cancer assessment for Radon 222 conducted in September 2002 did not identify any critical new studies. IRIS users who know of important new studies may provide that information to the IRIS Hotline at hotline.iris@epa.gov or (202)566-1676.

EPA Contacts:

Please contact the IRIS Hotline for all questions concerning this assessment or IRIS, in general, at (202)566-1676 (phone), (202)566-1749 (FAX) or hotline.iris@epa.gov (internet address).

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_III.  [reserved]
_IV.  [reserved]
_V.  [reserved]


_VI.  Bibliography

Substance Name -- Radon 222
CASRN -- 14859-67-7

Not available at this time.

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_VII.  Revision History

Substance Name -- Radon 222
CASRN -- 14859-67-7

Date
Section
Description
03/01/1988 II.A.1. Classification clarified
03/01/1988 II.B.1. Number rounded off
06/30/1988 II.D.3. Contacts changed
01/01/1989 II. Withdrawn pending further review
07/01/1989 II. Withdrawn; new assessment verified (in preparation)
01/01/1992 IV. Regulatory actions updated
11/01/1992 II. Work group review date added
03/01/1993 II. Work group review date added
05/01/1993 II. Work group review date added
07/01/1993 II. EPA contact changed
08/01/1995 II. EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995.
04/01/1997 III., IV., V. Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
12/03/2002 II. Screening-Level Literature Review Findings message has been added.

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_VIII.  Synonyms

Substance Name -- Radon 222
CASRN -- 14859-67-7
Last Revised -- 09/30/1987

14859-67-7
Radon 222
Radon, isotope of mass 222

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Substance Summary Index
Chronic Health Hazards for Non-Carcinogenic Effects
Reference Dose for Chronic Oral Exposure (RfD)

- Oral RfD Summary
- Principal and
  Supporting Studies
- Uncertainty and
  Modifying Factors
- Additional Studies/
  Comments
- Confidence in the
  Oral RfD
- EPA Documentation
  and Review

Reference Concentration for Chronic Inhalation Exposure (RfC)

- Inhalation RfC
  Summary
- Principal and
  Supporting Studies
- Uncertainty and
  Modifying Factors
- Additional Studies/
  Comments
- Confidence in the
  Inhalation RfC
- EPA Documentation
  and Review
Carcinogenicity Assessment for Lifetime Exposure
Evidence for Human Carcinogenicity

- Weight-of-Evidence
  Characterization
- Human
  Carcinogenicity Data
- Animal
  Carcinogenicity Data
- Supporting Data for
  Carcinogenicity

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

- Summary of Risk
  Estimates
- Dose-Response Data
- Additional Comments
- Discussion of
  Confidence

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

- Summary of Risk
  Estimates
- Dose-Response Data
- Additional Comments
- Discussion of
  Confidence

EPA Documentation, Review and, Contacts
  • Bibliography

  • Revision History

  • Synonyms
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