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Alternative names Return to top
Tubulointerstitial nephritis; Nephritis - interstitial; Acute interstitial (allergic) nephritisDefinition Return to top
Interstitial nephritis is a kidney disorder caused by inflammation of the tubules and the spaces between the tubules and the glomeruli.Causes, incidence, and risk factors Return to top
Interstitial nephritis involves inflammation of the spaces between the renal tubules and may include inflammation of the tubules. It may be a temporary lesion, most often associated with the effects of various medications on the kidney, or it may be chronic and progressive.Symptoms Return to top
Signs and tests Return to top
An examination may reveal edema or fluid overload, or signs of volume depletion, with abnormal sounds heard when listening with a stethoscope (auscultation) to the heart or lungs. The blood pressure commonly is high.Treatment Return to top
Treatment focuses on treating underlying causes and relieving symptoms. Avoiding the suspect medications may cause the symptoms to go away quickly.Expectations (prognosis) Return to top
Most often, interstitial nephritis is an acute but short-term disorder. On rare occasions it may cause permanent damage including chronic renal failure.Complications Return to top
Calling your health care provider Return to top
Call your health care provider if symptoms indicate interstitial nephritis may be present.Prevention Return to top
In many cases, the disorder may not be preventable. Avoiding or minimizing the use of associated medications may help reduce risk. Update Date: 10/17/2003 Updated by: Irfan A. Agha, M.D., Department of Medicine, Renal Division, St. Louis University, St. Louis, MO. Review provided by VeriMed Healthcare Network.
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Page last updated: 28 October 2004 |