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Definition Return to top
This is a blood test that measures the presence of cryoglobulins.
Cryoglobulins are abnormal proteins. At temperatures below normal body temperature (98.6 degrees F or 37 degrees C), cryogloblins no longer stay suspended in the blood. Instead, they separate out, forming complexes that can block small blood vessels, especially in the face and hands.
How the test is performed Return to top
Blood is drawn from a vein, usually on the inside of the elbow or the back of the hand. The puncture site is cleaned with antiseptic, and an elastic band is placed around the upper arm to apply pressure and restrict blood flow through the vein. This causes veins below the band to fill with blood.
A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. During the procedure, the band is removed to restore circulation. Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.
For an infant or young child:
The area is cleansed with antiseptic and punctured with a sharp needle or a lancet. The blood may be collected in a pipette (small glass tube), on a slide, onto a test strip, or into a small container. Cotton or a bandage may be applied to the puncture site if there is any continued bleeding.
How to prepare for the test Return to top
There are no special preparations.How the test will feel Return to top
When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.Why the test is performed Return to top
This test is most often performed when symptoms indicate that a person's blood may contain cryoglobulins. Cryoglobulins are associated with several disorders. (See "What Abnormal Results Mean".)Normal Values Return to top
Normally, there are no cryoglobulins.What abnormal results mean Return to top
A positive test may indicate:What the risks are Return to top
Special considerations Return to top
There are many specific sub-types of cryoglobulins, and tests may determine the specific type present.
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Page last updated: 28 October 2004 |