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Definition Return to top
This is a test used to determine if there are antibodies to Campylobacter in the blood.How the test is performed Return to top
Blood is drawn from a vein, usually on the inside of the elbow or the back of the hand. The puncture site is cleaned with antiseptic, and an elastic band is placed around the upper arm to apply pressure and restrict blood flow through the vein. This causes veins below the band to fill with blood.
A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. During the procedure, the band is removed to restore circulation. Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.
For an infant or young child, the area is cleansed with antiseptic and punctured with a sharp needle or a lancet. The blood may be collected in a pipette (small glass tube), on a slide, onto a test strip, or into a small container. Cotton or a bandage may be applied to the puncture site if there is any continued bleeding.
Serology refers to the study of serum (the fluid portion of blood) for its antibody content. An antibody defends the body against bacteria, viruses, fungus, or other foreign bodies (antigens). Certain microbial cells stimulate the body to produce these antibodies during active infection. Antibody production increases during the course of infection.
In the initial stage of an illness, few antibodies may be detected. For this reason, serology tests are often repeated 10 days to 2 weeks after the initial sample. In the laboratory, the antibodies react with antigens in specific ways that can be used to confirm the identity of a specific microorganism.
There are several serology techniques that can be used depending on the suspected antibodies. Serology techniques include agglutination, precipitation, complement-fixation, fluorescent antibodies, and others.
How to prepare for the test Return to top
There is no special preparation.How the test will feel Return to top
When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.Why the test is performed Return to top
This test is used to detect the presence of antibodies to Campylobacter in the blood. Infection with Campylobacter can cause an infectious diarrheal illness.Normal Values Return to top
No antibodies to Campylobacter are present.What abnormal results mean Return to top
Abnormal results indicate antibodies against Campylobacter (the person has been exposed to Campylobacter). It is important to see an increase in the antibody titer from the beginning of the illness to several weeks later, to distinguish current illness from previous exposure.What the risks are Return to top
Special considerations Return to top
Serology tests are often repeated during the course of an illness to detect a rise in antibody titers. This rise helps to confirm an active infection. A low titer may indicate a previous infection rather than a current disease.
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Page last updated: 28 October 2004 |
