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EPC Reports
AHRQ Evidence Reports and Technology Assessments
Overview
In 1997, the Agency for Healthcare Research and Quality (AHRQ) launched its
initiative to promote evidence-based practice in everyday care through establishment of 12
Evidence-based Practice Centers (EPCs). The EPCs develop evidence reports and technology
assessments on clinical topics that are common, expensive, and/or are significant for the
Medicare and Medicaid populations. With this program, AHRQ became a "science
partner" with private and public organizations in their efforts to improve the
quality, effectiveness, and appropriateness of clinical care by facilitating the
translation of evidence-based research findings into clinical practice.
Development of Evidence Reports and Technology Assessments
The EPCs develop evidence reports and technology assessments based on rigorous,
comprehensive reviews of relevant scientific literature, emphasizing explicit and
detailed documentation of methods, rationale, and assumptions. These scientific
syntheses may include meta-analyses and cost analyses. All EPCs collaborate with
other medical and research organizations so that a broad range of experts
is included in the development process. For additional information, please see the
AHRQ Web site.
Available Reports
Following is a list of EPC reports currently available online. Links to the
Summary, Full-text Evidence Report, and Download Files for the Evidence Report
(where available) are provided. Additional titles will be added to this list as
they become available.
Evidence Reports:
- Report No. 1. Systematic review of the literature regarding
the diagnosis of sleep apnea. Rockville, MD: AHCPR, 1998 Dec.
Summary
Full-text Report
- Report No. 2. Rehabilitation for traumatic brain injury.
Rockville, MD: AHCPR, 1999 Feb.
Summary
Full-text Report
- Report No. 2 (Supplement). Rehabilitation for traumatic brain injury in children
and adolescents. Rockville, MD: AHCPR, 1999 Feb.
Summary
Full-text Report
- Report No. 3. Pharmacotherapy for alcohol dependence.
Rockville, MD: AHCPR, 1999 Jan.
Summary
Full-text Report
- Report No. 4. Relative effectiveness and cost-effectiveness
of methods of androgen suppression in the treatment of advanced prostatic cancer.
Rockville, MD: AHCPR, 1999 May.
Summary
Full-text Report
- Report No. 5. Evaluation of cervical cytology.
Rockville, MD: AHCPR, 1999 Feb.
Summary
Full-text Report
- Report No. 6. Prevention and management of urinary tract
infections in paralyzed persons. Rockville, MD: AHCPR, 1999 Feb.
Summary
Full-text Report
- Report No. 7. Treatment of depression: newer pharmacotherapies.
Rockville, MD: AHCPR, 1999 Feb.
Summary
Full-text Report
- Report No. 8. Diagnosis and treatment of swallowing disorders
(dysphagia) in acute-care stroke patients. Rockville, MD: AHCPR, 1999 Jul.
Summary
Full-text Report
- Report No. 9. Diagnosis and treatment of acute bacterial
rhinosinusitis. Rockville, MD: AHCPR, 1999 Mar.
Summary
Full-text Report
- Report No. 9 (Supplement). Diagnosis and treatment of
uncomplicated acute sinusitis in children. Rockville, MD: AHCPR, 2000 Oct.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 10. An evaluation of beta-blockers, calcium antagonists,
nitrates, and alternative therapies for stable angina. Rockville, MD: AHCPR, 1999 Nov.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 11. Treatment of attention-deficit/hyperactivity
disorder. Rockville, MD: AHCPR, 1999 Dec.
Summary
Full-text Report
- Report No. 12. Management of new onset atrial fibrillation.
Rockville, MD: AHRQ, 2000 May.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 13. Determinants of disability in patients
with chronic renal failure. Rockville, MD: AHRQ, 2000 May.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 14. Management of chronic hypertension during pregnancy.
Rockville, MD: AHRQ, 2000 Aug.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 15. Management of acute otitis media.
Rockville, MD: AHRQ, 2000 Jun.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 16. Anesthesia management during cataract surgery.
Rockville, MD: AHRQ, 2000 Aug.
Summary
Full-text Report (Volume 1) and
Full-text Report (Volume 2) /
Full-text Report (File Download)
- Report No. 17. Management of acne. Rockville, MD: AHRQ, 2001 Mar.
Summary
Full-text Report (Volume 1) and
Full-text Report (Volume 2) /
Full-text Report (File Download)
- Report No. 18. Management of preterm labor. Rockville, MD: AHRQ, 2000 Oct.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 19. Management of acute exacerbations of chronic
obstructive pulmonary disease. Rockville, MD: AHRQ, 2000 Sep.
Summary
Full-text Report (File Download)
- Report No. 20. Garlic: effects on cardiovascular risks and disease,
protective effects against cancer, and clinical adverse effects.
Rockville, MD: AHRQ, 2000 Oct.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 21. Milk thistle: effects on liver disease and cirrhosis
and clinical adverse effects. Rockville, MD: AHRQ, 2000 Sep.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 22. Prevention of venous thromboembolism after injury.
Rockville, MD: AHRQ, 2000 Sep.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 23. Criteria for weaning from mechanical ventilation.
Rockville, MD: AHRQ, 2000 Jun.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 24. Telemedicine for the Medicare population.
Rockville, MD: AHRQ, 2001 Feb.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 24 (Supplement). Telemedicine for the
Medicare population: Pediatric, obstetric and clinician-indirect home interventions.
Rockville, MD: AHRQ, 2001 Aug.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 25. Efficacy of interventions to modify dietary
behavior related to cancer risk. Rockville, MD: AHRQ, 2000 Nov.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 26. Evaluation of technologies for identifying
acute cardiac ischemia in emergency departments. Rockville, MD: AHRQ, 2000 Sep.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 27. Treatment of pulmonary disease following
cervical spinal cord injury. Rockville, MD: AHRQ, 2001 Jun.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 28. Osteoporosis in postmenopausal women:
diagnosis and monitoring. Rockville, MD: AHRQ, 2001 Feb.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 29. Use of epoetin for anemia in chronic renal failure.
Rockville, MD: AHRQ, 2001 Aug.
Summary
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Full-text Report (File Download)
- Report No. 30. Uses of epoetin for anemia in oncology.
Rockville, MD: AHRQ, 2001 Mar.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 31. Prediction of risk for patients with unstable angina.
Rockville, MD: AHRQ, 2000 Aug.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 32. Treatment of degenerative lumbar spinal stenosis.
Rockville, MD: AHRQ, 2001 Mar.
Summary
Full-text Report (Volume 1)
and Full-text Report (Volume 2) /
Full-text Report (File Download)
- Report No. 33. Diagnosis and management of specific breast abnormalities.
Rockville, MD: AHRQ, 2001 Apr.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 34. Management of uterine fibroids.
Rockville, MD: AHRQ, 2001 Jan.
Summary
Full-text Report (Volume 1)
and Full-text Report (Volume 2) /
Full-text Report (File Download)
- Report No. 35. Management of cancer pain. Rockville, MD: AHRQ, 2001 Jan.
Summary
Full-text Report (Volume 1) and
Full-text Report (Volume 2) /
Full-text Report (File Download)
- Report No. 36. Diagnosis and management of dental caries.
Rockville, MD: AHRQ, 2001 Feb.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 37. Management of dental patients who are HIV positive.
Rockville, MD: AHRQ, 2001 Mar.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 38. Surgical treatment of coexisting cataract and glaucoma.
Rockville, MD: AHRQ, 2001 Jun.
Summary
Full-text Report (File Download)
- Report No. 39. Management of newly diagnosed patients with epilepsy:
a systematic review of the literature. Rockville, MD: AHRQ, 2001 Feb.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 40. Mind-body interventions for gastrointestinal conditions.
Rockville, MD: AHRQ, 2001 Mar.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 41. Ayurvedic interventions for diabetes mellitus:
a systematic review. Rockville, MD: AHRQ, 2001 Jun.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 42. Defining and managing chronic fatigue syndrome.
Rockville, MD: AHRQ, 2001 Sep.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 43. Making health care safer. A critical analysis of
patient safety practices. Rockville, MD: AHRQ, 2001 Jul.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 44. Management of chronic asthma. Rockville, MD: AHRQ, 2001 Sep.
Summary
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Full-text Report (File Download)
- Report No. 45. Management of chronic central neuropathic pain
following traumatic spinal cord injury. Rockville, MD: AHRQ, 2001 Sep.
Summary
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Full-text Report (File Download)
- Report No. 46. Impact of cancer-related decision aids.
Rockville, MD: AHRQ, 2002 Jul.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 47. Systems to rate the strength of scientific
evidence. Rockville, MD: AHRQ, 2002 Mar.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 48. Cardiovascular effects of epinephrine in
hypertensive dental patients. Rockville, MD: AHRQ, 2002 Mar.
Summary
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Full-text Report (File Download)
- Report No. 49. Effectiveness and cost-effectiveness of echocardiography and
carotid imaging in management of stroke. Rockville, MD: AHRQ, 2002 Jul.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 50. Endoscopic retrograde cholangiopancreatography.
Rockville, MD: AHRQ, 2002 Jan.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 51. Training of clinicians for public health events
relevant to bioterrorism preparedness. Rockville, MD: AHRQ, 2001 Dec.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 52. Criteria for determining disability in speech-language disorders.
Rockville, MD: AHRQ, 2002 Jan.
Summary
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Full-text Report (File Download)
- Report No. 53. Management of prolonged pregnancy.
Rockville, MD: AHRQ, 2002 Mar.
Summary
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Full-text Report (File Download)
- Report No. 54. Management of allergic and nonallergic rhinitis.
Rockville, MD: AHRQ, 2002 May.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 55. Diagnosis, natural history, and late effects of otitis media with
effusion. Rockville, MD: AHRQ, 2002 Jun.
Summary
Full-text Report (File Download)
- Report No. 56. Management of clinically inapparent adrenal mass.
Rockville, MD: AHRQ, 2002 Feb.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 57. Diagnosis and treatment of Parkinson's disease:
A systematic review of the literature. Rockville, MD: AHRQ, 2003 Jun.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 58. Autopsy as an outcome and performance measure.
Rockville, MD: AHRQ, 2002 Oct.
Summary
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Full-text Report (File Download)
- Report No. 59. Bioterrorism preparedness and response: Use of
information technologies and decision support systems. Rockville, MD: AHRQ, 2002 Jul.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 60. Management of chronic hepatitis C.
Rockville, MD: AHRQ, 2002 Jun.
Summary
Full-text Report (File Download)
- Report No. 61. Management of cancer symptoms: pain, depression, and fatigue.
Rockville, MD: AHRQ, 2002 Jul.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 62. Diagnosis and treatment of worker-related
musculoskeletal disorders of the upper extremity. Rockville, MD: AHRQ, 2002.
Summary
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Full-text Report (File Download)
- Report No. 63. Utility of blood pressure monitoring outside of the clinic setting.
Rockville, MD: AHRQ, 2002 Nov.
Summary
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Full-text Report (File Download)
- Report No. 64. S-adenosyl-L-methionine for treatment of depression,
osteoarthritis, and liver disease. Rockville, MD: AHRQ, 2002 Aug.
Summary
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Full-text Report (File Download)
- Report No. 65. Management of neonatal hyperbilirubinemia.
Rockville, MD: AHRQ, 2002 Nov.
Summary
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Full-text Report (File Download)
- Report No. 66. Systematic review of the current literature related to disability
and chronic fatigue syndrome. Rockville, MD: AHRQ, 2002 Dec.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 67. Management of allergic rhinitis in the working-age population.
Rockville, MD: AHRQ, 2003 Feb.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 68. Diagnosis and treatment of deep venous thrombosis and pulmonary
embolism. Rockville, MD: AHRQ, 2003 Jan.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 69. Management of bronchiolitis in infants and children.
Rockville, MD: AHRQ, 2003 Jan.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 70. Criteria for determining disability in infants and children: low
birth weight. Rockville, MD: AHRQ, 2003 Mar.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 71. Vaginal birth after cesarean (VBAC). Rockville, MD: AHRQ, 2003 Mar.
Summary
Full-text Report (File Download)
- Report No. 72. Criteria for determining disability in infants and children:
failure to thrive. Rockville, MD: AHRQ, 2003 Mar.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 73. Criteria for determining disability in infants and children: short stature.
Rockville, MD: AHRQ, 2003 Mar.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 74. The effect of health care working conditions on patient safety.
Rockville, MD: AHRQ, 2003 Feb.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 75. Effect of the supplemental use of antioxidants vitamin C, vitamin E,
and coenzyme Q10 for the prevention and treatment of cancer. Rockville, MD: AHRQ, 2003 Oct.
Summary
Full-text Report (File Download)
- Report No. 76. Ephedra and ephedrine for weight loss and athletic performance
enhancement: clinical efficacy and side effects. Rockville, MD: AHRQ, 2003 Mar.
Summary
Full-text Report (File Download)
- Report No. 77. Management of treatment-resistant epilepsy.
Rockville, MD: AHRQ, 2003 Apr.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 78. Best-case series for the use of immuno-augmentation therapy and
naltrexone for the treatment of cancer. Rockville, MD: AHRQ, 2003 Apr.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 79. Diffusion and dissemination of evidence-based cancer control interventions.
Rockville, MD: AHRQ, 2003 May.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 80. Results of systematic review of research on diagnosis and treatment of coronary heart disease in women. Rockville, MD: AHRQ, 2003 May.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 81. Diagnosis and treatment of coronary heart disease in women: systematic reviews of
evidence on selected topics. Rockville, MD: AHRQ, 2003 May.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 82. Pharmacologic management of heart failure and left ventricular systolic dysfunction: effect in female, black, and diabetic patients, and cost-effectiveness. Rockville, MD: AHRQ, 2003 July.
Summary
Full-text Report (File Download)
- Report No. 83. Effect of supplemental antioxidants vitamin C, vitamin E, and coenzyme Q10 for the prevention and treatment of cardiovascular disease.
Rockville, MD: AHRQ, 2003 Jul.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 84. Use of glycated hemoglobin and microalbuminuria in the monitoring of diabetes mellitus.
Rockville, MD: AHRQ, 2003 Jul.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 85. Hyperbaric oxygen therapy for brain injury, cerebral palsy, and stroke.
Rockville, MD: AHRQ, 2003 Sep.
Summary
Full-text Report (File Download)
- Report No. 86. Total knee replacement. Rockville, MD: AHRQ, 2003 Nov.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 87. Literacy and health outcomes. Rockville, MD: AHRQ, 2004 Jan.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 88. Effectiveness of antimicrobial adjuncts to scaling and root-planing
therapy for periodontitis. Rockville, MD: AHRQ, 2004 Jan.
Summary
Full-text Report (File Download)
- Report No. 89. Effects of omega-3 fatty acids on lipids and glycemic control in type II
diabetes and the metabolic syndrome and on inflammatory bowel disease, rheumatoid arthritis, renal disease,
systemic lupus erythematosus, and osteoporosis. Rockville, MD: AHRQ, 2004 Mar.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 90. Strategies for improving minority healthcare quality. Rockville, MD: AHRQ, 2004 Jan.
Summary
Full-text Report (File Download)
- Report No. 91. Health effects of omega-3 fatty acids on asthma. Rockville, MD: AHRQ, 2004 Mar.
Summary
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Full-text Report (File Download)
- Report No. 92. Effects of omega-3 fatty acids on arrhythmogenic mechanisms in animal and
isolated organ/cell culture studies. Rockville, MD: AHRQ, 2004 Mar.
Summary
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Full-text Report (File Download)
- Report No. 93. Effects of omega-3 fatty acids on cardiovascular risk factors and
intermediate markers of cardiovascular disease. Rockville, MD: AHRQ, 2004 Mar.
Summary
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Full-text Report (File Download)
- Report No. 94. Effects of omega-3 fatty acids on cardiovascular disease. Rockville, MD: AHRQ, 2004 Mar.
Summary
Full-text Report (File Download)
- Report No. 95. Training of hospital staff to respond to a mass casualty incident. Rockville, MD: AHRQ, 2004 Apr.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 97. Pharmacological treatment of dementia. Rockville, MD: AHRQ, 2004 Apr.
Summary
Full-text Report (File Download)
- Report No. 98. Islet transplantation in patients with type 1 diabetes mellitus. Rockville, MD: AHRQ, 2004 Jul.
Summary
Full-text Report (File Download)
- Report No. 99. Community-based participatory research: assessing the evidence. Rockville, MD: AHRQ, 2004 Aug.
Summary
Full-text Report (File Download)
- Report No. 100. Criteria to determine disability related to multiple sclerosis. Rockville, MD: AHRQ, 2004 May.
Summary
Full-text Report (File Download)
- Report No. 101. Economic incentives for preventive care. Rockville, MD: AHRQ, 2004 Aug.
Summary
Full-text Report (File Download)
- Report No. 102. Effectiveness of behavioral interventions to modify physical activity behaviors in general populations and cancer
patients and survivors. Rockville, MD: AHRQ, 2004 Jun.
Summary
Full-text Report (File Download)
- Report No. 103. Pharmacological and surgical treatment of obesity. Rockville, MD: AHRQ, 2004 Jul.
Summary
Full-text Report /
Full-text Report (File Download)
- Report No. 104. Celiac disease. Rockville, MD: AHRQ, 2004 Jun.
Summary
Full-text Report (File Download)
- Report No. 105. Measuring the quality of breast cancer care in women. Rockville, MD: AHRQ, 2004 Sep.
Summary
Full-text Report (File Download)
Evidence Technical Reviews:
- Report No. 1. Colorectal cancer screening. Rockville, MD: AHRQ, 1998 May.
Summary
Technical Review
- Report No. 3. Diagnosis of attention-deficit/hyperactivity disorder.
Rockville, MD: AHRQ, 1999 Oct May.
Summary
- Report No. 4. Refinement of the HCUP quality indicators.
Rockville, MD: AHRQ, 2001 May.
Summary
Technical Review (File Download)
- Report No. 5. Measures of patient safety based on hospital administrative
data -- the patient safety indicators. Rockville, MD: AHRQ, 2002 Aug.
Technical Review (File Download)
- Report No. 6. Current validity of AHRQ clinical practice guidelines.
Rockville, MD: AHRQ, 2002 Sep.
Technical Review (File Download)
- Report No. 7. Determinants of increases in medicare expenditures for physicians'
services. Rockville, MD: AHRQ, 2003 Oct.
Technical Review (File Download)
- Report No. 8. Meta-regression approaches: what, why, when, and how?. Rockville, MD: AHRQ, 2004 Mar.
Technical Review (File Download)
- Report No. 9. Closing the quality gap: volume 1 -- Series overview and methodology.
Rockville, MD: AHRQ, 2004 Aug.
Technical Review (File Download)
- Report No. 10. Strategies to support quality-based purchasing: A review of the evidence.
Rockville, MD: AHRQ, 2004 Jul.
Summary
Technical Review (File Download)