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Test Guidelines/Acute Toxicity -
Acute Oral Toxicity Up-And-Down-Procedure
Note:
The acute oral toxicity portion of this page is being updated. Please
revisit this page on a frequent basis to determine if additional materials
are available.
- User
Documentation for the AOT425StatPgm Program (Users should read this
file before downloading the AOT425StatPgm file - revised July 2003)
- (9.11 MB - PDF)
- AOT425StatPgm
(This is a self-extracting zip file which will install the program on
your computer in two steps) - (1.84mb - exe) Note:
This is to confirm that use of the computer program, AOT425StatPgm,
developed by Westat for the US EPA , is freely given and there are no
licensing restrictions in connection with its use. The user is cautioned
to read the User Documentation regarding any limitations an applicability
and hardware requirements.
- AOT
Test Data Set (This is a zip file which contains 15 test data sets,
a result table, and instructions for their use to verify proper installation
of the AOT425StatPgm program) (114kb - Zip
)
- QA
Testing for the AOT425StatPgm Program - (936 KB, PDF)
- Simulation
Results for the AOT425StatPgm Program - (1.7 MB, PDF)
- Toxicology
Guidance: Performance of the Up-and-Down Procedure - (103 KB, PDF)
- OECD
Test Guideline 425: Acute Oral Toxicity - Up-and-Down Procedure
- (413k - PDF)
- Crosswalk
of Paragraphs: OPPTS 870.1100 versus OECD 425 Acute Oral Toxicity: Up-and-Down
Procedure - (13 KB, PDF)
- OPPTS
Harmonized Test Guideline 870.1100 Acute Oral Toxicity (189 KB,
PDF)
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