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Improving the Drug Development Process

A family of proteins, including the cancer target protein NSD2, surround a cell’s nucleosome.
New Approach to Identify Potential Cancer Drugs

NCATS researchers develop a series of assays (tests) to identify compounds that disrupt a driver of several cancers.

NCATS Robots
Accelerating Drug Discovery

Using NCATS’ ASPIRE program in pre-clinical drug discovery, scientists can study unexplored biologically active chemical space through integrating automated synthetic chemistry, high-throughput biology and artificial intelligence technologies.

Target Identification & Validation

Developing new approaches and technologies to identify and validate potential drug targets in a more efficient and predictable way.

Assay Development & Screening

Enhancing testing systems to assess the effects of chemical compounds on cellular, molecular or biochemical processes of interest.

Probe Development & Lead Optimization

Creating probes to investigate biological processes and optimizing them to become potential drug candidates.

Core Technologies

Using state-of-the-art resources to enable the ongoing operation of all NCATS translational research activities.

Target Identification & Validation

Developing new approaches and technologies to identify and validate potential drug targets in a more efficient and predictable way.

Assay Development & Screening

Enhancing testing systems to assess the effects of chemical compounds on cellular, molecular or biochemical processes of interest.

Probe Development & Lead Optimization

Creating probes to investigate biological processes and optimizing them to become potential drug candidates.

Core Technologies

Using state-of-the-art resources to enable the ongoing operation of all NCATS translational research activities.

Work with Us

NCATS pre-clinical programs and resources focus on key obstacles and inefficiencies in the translational process, overcoming bottlenecks that slow the development of new treatments for patients.

Learn more about how to access NCATS programs and expertise.

Learn more about NCATS’ Achievements in Advancing Translational Sciences.

Translational Science Spectrum

Learn more about the science of translation.