(Emergency Room Info) (After Reye's Syndrome) (Reporting A Case)

Treatment of Reye's Syndrome

The treatment of Reye's syndrome varies. Reye's Syndrome is an acute, rapidly progressive disease. It should be treated as a medical emergency, and time is of the utmost importance. The chance of recovery is greatly increased when it is treated in its earliest stages. To date there  is no cure for the disease. Successful management of the disease depends on early diagnosis. Therapy is primarily directed to protect the brain against irreversible damage by reducing the brain swelling.

People with Reye's Syndrome require the services of an intensive care unit and physicians and nurses experienced in the treatment of the disease. A person with Reye's Syndrome should be transferred to a teaching hospital or a children's hospital. If this is not possible, immediate phone consultation with a teaching hospital or children's hospital. The majority of individuals with Reye's Syndrome are children; however, cases have been reported in adults.


If Reye's Syndrome is suspected (ER Info), two liver function tests should be done immediately:
SGOT (SAT)     SGPT(ACT)

 

The results of these tests are commonly available within 2-3 hours. Abnormal SGOT and SGPT strongly suggest a diagnosis of Reye's Syndrome. Immediate further diagnostic testing will give a definite diagnosis.

In 1963 when Reye's Syndrome was discovered, the death rate was at 80%. In 1973, the mortality rate was estimated around 40%, and in 1983 it was lowered to 31%. In 1996, the mortality rate increased to 50%. It is believed that this increase occurred due to misdiagnosis of Reye's Syndrome.

Recovery is related to the severity of the brain swelling. Some people recover completely. Others may sustain brain damage, extending from slight to severe brain dysfunction. Those who progress rapidly through the stages and lapse into a coma have a poorer prognosis than those with a less severe disease. All people surviving Reye's Syndrome should be evaluated using quantitative psychological and neuropsychological tests.

For those survivors with disabilities, please refer to resources including Crippled Children's Services, State Developmental Disabilities Agencies, child development clinics, local school systems, and health departments. Parents also should familiarize themselves with Equal Opportunities for Individuals with Disabilities Act, Americans with Disabilities Act of 1990, Title 42, Chapter 126, Sec. 12101-12213 available through public libraries.

 

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E-mail: nrsf@reyessyndrome.org
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