Case Study
Pretest
Challenge question
Case
Study
A 55-year-old female
child care worker comes to your office concerned about a nontender
thyroid mass that has slowly grown over the last 2 years. She is
worried that this condition could be passed on to her daughter,
who is pregnant.
Your patient was born
in 1945 in Washington State. She grew up on a farm near the Hanford
Nuclear Reservation, where her father worked as a machinist during
World War II. The family history reveals that the woman lives with
her husband of 41 years; her daughter, born in 1963, who is 6 months
pregnant; and her daughter's husband. They have lived in your community
for the last 12 years, in a single home in a low income area of
town.
The patient's past medical
history is noncontributory, and her family history is unremarkable.
Her father died at age 84 of a myocardial infarction, and her mother
died of colon cancer at age 77. The patient has no family history
of thyroid disease or of other endocrine disease. She has two brothers
and a sister; all are reportedly in good health.
Your patient does not
have symptoms consistent with hyperthyroidism or hypothyroidism;
does not smoke and has not smoked in the past, but she occasionally
drinks alcohol. She does not have any past workplace or hobby chemical
exposures, and she has not received any therapeutic radiation exposures.
Pretest
(a) Which
organ system is considered the critical organ for exposure to I-131?
(b)
What are the main routes of human internal exposure for
I-131?
(c) What are the most
significant health effects from exposure to
I-131?
(d) Which group is
most at risk for health effects from exposure to
I-131, and why?
Challenge
question
1. What have
been the main sources of I-131 in the environment?
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