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Assisted Reproductive 
Technology Reports 

2001 Assisted Reproductive Technology Success Rates
National Summary and Fertility Clinic Reports
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The 2001 report of pregnancy success rates is the seventh report to be issued under the Fertility Clinic Success Rate and Certification Act. The report includes a national overview that uses information from 384 U.S. fertility clinics to provide an in-depth picture of the type, number, and outcome of ART cycles performed in U.S. clinics. The report also includes individual clinic tables that provide ART success rates and other information from each clinic that submitted and verified its 2001 data and appendixes containing the results of data validation visits, technical notes, a glossary of terms, and contact information for reporting and nonreporting clinics in the United States.
Previous ART Reports
2000 | 1999 | 1998–1995 (PDF format only)
 
new icon Assisted Reproductive Technology Surveillance United States, 2001 | adobe PDF logo View PDF 568KB
With the advent of assisted reproductive technology (ART) more than 20 years ago, American couples increasingly have turned to such treatments to overcome fertility problems. Nationwide, 107,587 procedures were performed in 2001 by ART— fertility treatments in which the egg and sperm are handled in the laboratory— resulting in 29,344 live births and 40,687 infants. This report expands information on geography and determinants of both ART success and multiple birth risks beyond that which appears in the 2001 Assisted Reproductive Technology Success Rates: National Summary and Fertility Clinic Report. Source: MMWR, April 30, 2004/53(SS01);1–20.

Previous ART Surveillance Summary
2000

Use of Assisted Reproductive Technology — United States, 1996 and 1998
Since 1983, when the first infant was conceived from in vitro fertilization (IVF) in the United States, the use of IVF and related procedures (assisted reproductive technology [ART]) has increased substantially.

Contribution of Assisted Reproductive Technology and Ovulation-Inducing Drugs to Triplet and Higher-Order Multiple Births— United States, 1980–1997 
Pregnancies associated with assisted reproductive technology (ART) and drugs that induce ovulation are more likely to result in multiple births than spontaneously conceived pregnancies in the United States. Triplet and higher-order multiple births are at greater risk than singleton births to be preterm, low or very low birth weight, which may result in higher infant morbidity and mortality. This report estimates the connection between these birth outcomes and ART and ovulation-inducing drugs in 1996 and 1997. It also summarizes the trends that indicate ART and the use of ovulation-inducing drugs have increased the ratio of triplet and higher-order multiple births during the 1980s and most of the 1990s. Source: MMWR, June 23, 2000/ 49(24);535-8.

Live-Birth Rates and Multiple-Birth Risk Using In Vitro Fertilization*
To maximize birth rates, physicians who perform in vitro fertilization (IVF) often transfer multiple embryos, but this increases the multiple-birth risk. Live-birth and multiple-birth rates may vary by patient age and embryo quality. One marker for embryo quality is cryopreservation of extra embryos (if embryos are set aside for cryopreservation, higher quality embryos may have been available for transfer). The study found that, the risk of multiple births from IVF varies by maternal age and number of embryos transferred. Embryo quality was not related to multiple birth risk but was associated with increased live-birth rates when fewer embryos were transferred. Source: JAMA. 1999;282:1832–1838.  

Implementation of the Fertility Clinic Success Rate and Certification Act of 1992: A Model Program for the Certification of Embryo Laboratories  
A Model Program for the Certification of Embryo Laboratories The Fertility Clinic Success Rate and Certification Act of 1992 (Pub. L. 102-493, 42 U.S.C. 263a-1 et seq.) required the Secretary, Department of Health and Human Services, through the CDC, to develop a model program for the certification of embryo laboratories, to be carried out voluntarily by interested states. This notice sets forth the model certification program requirements, including definitions, administrative requirements, and embryo laboratory standards. The model program incorporates comments received by CDC on the proposed model certification program that was published in the Federal Register on November 6, 1998 (63 FR 60178). From the Division of Laboratory Systems, Public Health Practice Program Office, CDC.

Assisted Reproductive Technology: Embryo Laboratory 
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This site links to the (1) January 1999 report entitled Survey of Assisted Reproductive Technology: Embryo Laboratory Procedures and Practices (119 pages); and (2) Proposed Model Certification Program for Embryo Laboratories as required by the Fertility Clinic Success Rate and Certification Act of 1992. From the Division of Laboratory Systems, Public Health Practice Program Office, CDC.

Pregnancy-related death associated with heparin and aspirin treatment for infertility, 1996 | adobe PDF logo View PDF 268KB   
In 1998,
CDC investigated the death of a pregnant woman who had undergone in-vitro fertilization and aspirin and heparin therapy. Although researchers could not conclude that the woman's death was caused by the therapy, the potential for bleeding associated with aspirin and heparin warrants vigorous scientific investigation and debate before it is recommended for routine use among in-vitro fertilization patients. Source: MMWR, May 15, 1998 /Vol. 47, No.18.

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This page last reviewed August 20, 2004.

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