Fact Sheets
Infection Control
Last Updated: August 5, 1999
CDC is not a regulatory agency, thus CDC recommendations
on infection control are not regulations. For regulations in your
area, contact your state or local Occupational
Safety and Health Administration (OSHA).
Overview of Infection Control Measures
An effective infection control program requires the
early detection of TB and the prompt isolation and treatment of
persons with TB. The primary emphasis of the TB infection control
plan should be on achieving these three goals. In all health-care
facilities, particularly those in which persons who are at high
risk for TB work or receive care, policies and procedures for TB
control should be developed, reviewed periodically, and evaluated
for effectiveness to determine the actions necessary to minimize
the risk for transmission of M. tuberculosis.
The TB infection control program should be based on
a hierarchy of control measures. The first level of the hierarchy,
and that which affects the largest number of persons, is using administrative
measures intended primarily to reduce the risk of exposing uninfected
persons to persons who have infectious TB. These measures include
(a) developing and implementing effective written policies and protocols
to ensure the rapid identification, isolation, diagnostic evaluation,
and treatment of persons likely to have TB; (b) implementing effective
work practices among health care workers in the health-care facility
(e.g., correctly wearing respiratory protection and keeping doors
to isolation rooms closed); (c) educating, training, and counseling
health care workers about TB; and (d) screening health care workers
for TB infection and disease.
The second level of the hierarchy is the use of engineering
controls to prevent the spread and reduce the concentration of infectious
droplet nuclei. These controls include (a) direct source control
using exhaust ventilation, (b) controlling the direction of airflow
to prevent the contamination of air in areas adjacent to the infectious
source, (c) diluting and removing contaminated air via general ventilation,
and (d) cleaning the air via air filtration or ultraviolet germicidal
irradiation.
The first two levels of the hierarchy minimize the
number of areas in the health-care facility where exposure to infectious
TB may occur, and they reduce, but do not eliminate, the risk in
those few areas where exposure to M. tuberculosis can still
occur (e.g., rooms in which patients with known or suspected infectious
TB are being isolated and treatment rooms in which cough-inducing
or aerosol-generating procedures are performed on such patients).
Because persons entering such rooms may be exposed to M. tuberculosis,
the third level of the hierarchy is the use of personal respiratory
protective equipment in these and certain other situations in which
the risk for infection with M. tuberculosis may be relatively
higher. For current guidelines on respiratory protection, please
order CDC Fax Document #250135, Respiratory
Protection, or order the complete infection control guidelines.
Determining the Infectiousness of TB Patients
In general, patients who have suspected or confirmed
active TB should be considered infectious if (a) they are coughing,
they are undergoing cough-inducing procedures, or their sputum smears
are positive for acid-fast bacilli; and (b) they
are not receiving therapy, have just started therapy, or have a
poor clinical or bacteriologic response to therapy.
TB patients are no longer considered infectious if
-
they are on adequate therapy,
-
they have had a favorable clinical response to
therapy, and
-
they have three consecutive negative sputum smear
results.
For more information
For more information about implementing CDC guidelines,
call your state health department.
To order the following publication, call the CDCs
Voice and Fax Information System (recording) toll free at (888)
232-3228, then press options 2, 5, 1, 2, 2 (Note: You may select
these options at any time without listening to the complete message).
Request the publication number of the document you would like to
order. You may also visit the Division of TB Eliminations
Web site at http://www.cdc.gov/nchstp/tb.
Publication # 00-5856. CDC. Guidelines for preventing the transmission
of Mycobacterium tuberculosis in health-care facilities,
1994. MMWR
1994;43(No.RR-13).
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